Biochem/physiol Actions

Product does not compete with ATP.

Primary TargetMethionine amino-peptidase 2

General description

Antiprotozoal agent and angiogenesis inhibitor. Acts as an inhibitor of methionine amino-peptidase 2.

An inhibitor of angiogenesis. Has selective cytostatic effects against ras transformed cells (IC₅₀ = 10 pM). Antiprotozoal agent active against sporozoan parasites in bees and myxozoan parasites in fish.

Antiprotozoal agent and angiogenesis inhibitor.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Zhang, P., et al. 2002. J. Biomed. Sci.9, 34.Stepien, H., et al. 1996. J. Endocrinol.150, 99.Abrams, J.S., et al. 1994. Cancer74, 1164.Jenkins, D.C., et al. 1993. Br. J. Cancer68, 856.Le Querrec, A., et al. 1993. Baillieres Clin. Hematol.6, 711.Molnar, K. 1993. Acta Vet. Hung. 41, 51.Kusada, M., et al. 1991. Biochem. Biophys. Res. Commun. 174, 1070.Brackett, J.M., et al. 1988. J. Agric. Food Chem.36, 762.

Packaging

Packaged under inert gas

500 µg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Warning

Toxicity: Harmful (C)